Bone loss and fracture risk

Bone loss and fracture risk associated with cancer therapy.

BACKGROUND Cancer patients experience osteoporosis resulting from accelerated loss of bone mineral density (BMD) caused by their treatment. Such bone loss greatly increases the risk for fracture and can have other serious effects on quality of life. METHODS In the current report, the author focuses on studies of cancer therapy-associated bone loss, its prevalence and pathogenesis, and resulti...

Inflammation, bone loss and fracture risk in spondyloarthritis

Osteoporosis (ie, low bone mineral density) is common in ankylosing spondylitis, related to both systemic inflammation and decreased mobility. Vertebral fracture risk is increased; acute back pain in these patients is not always a flare-up of the disease, as it can be related to bone complications. Intervertebral disc fractures in the ankylosed spine are associated with severe neurological comp...

Bone density and fracture risk.

steoporosis, most simply and elegantly defined as “too little bone in the bone”, is generally the result of progressive bone loss which, for all practical purposes, starts at menopause in women and at about the age of 50 years in men. Because women have a lower bone organ density than men and then lose bone more rapidly, and also because women live longer, osteoporotic fractures, particularly a...

Osteoporosis and fracture risk: bone matrix quality.

Introduction--Bone turnover and fracture risk.